Issues

• [BUG]: AlphaFold pLDDT coloring in the 3D structure viewer doesn't match its legend

  bug
  cBioPortal/cbioportal#12439 · Filter by author Pradyuman-aviator opened on Oct 20, 2026
  4

• mRNA tab - Some ideas of adding options to better support identify genes

  enhancement
  cBioPortal/cbioportal#12435 · Filter by author onursumer opened on Oct 19, 2026
  1

  

• Locked studies (status=0) don't force readPermission: false in /api/studies

  bug
  cBioPortal/cbioportal#12430 · Filter by author alisman opened on Oct 16, 2026
  3

• [BUG] Study search dropdown toggle button lacks accessible name (WCAG 4.1.2)

  triage
  cBioPortal/cbioportal#12425 · Filter by author Rucha0901 opened on Oct 16, 2026

• readPermission is true for locked (status=0) studies in /api/studies

  bug
  cBioPortal/cbioportal#12419 · Filter by author alisman opened on Oct 15, 2026
  1

• Title: Expression and generic assay enrichment tables hide genes whose group mean is exactly 0

  triage
  cBioPortal/cbioportal#12417 · Filter by author Pradyuman-aviator opened on Oct 15, 2026

• Paged API results are not invalidated when the underlying study changes

  discussion
  cBioPortal/cbioportal#12416 · Filter by author dippindots opened on Oct 14, 2026
  9

• [nepc_wcm_2016] Clarification of RNA-expression processing and negative values

  datasupport
  cBioPortal/cbioportal#12402 · Filter by author genomics-ccrtd-cau opened on Oct 9, 2026
  3

  

• Package cBioPortal as an installable Chrome/Chromium app (PWA)

  triage
  cBioPortal/cbioportal#12385 · Filter by author jjgao opened on Oct 1, 2026
  1

• Study View: Promote ClickHouse-backed custom data endpoints out of /not-ready-yet/

  discussionfeature
  cBioPortal/cbioportal#12380 · Filter by author Injora opened on Sep 30, 2026
  1

  

• [Bug] Gene panel matrix export removes repeated study ID from profile names

  triage
  cBioPortal/cbioportal#12362 · Filter by author 1sakshm opened on Sep 23, 2026
  3

• [Bug] Study export removes repeated study identifiers from profile and case-list IDs

  bug
  cBioPortal/cbioportal#12350 · Filter by author 1sakshm opened on Sep 19, 2026

• Issues with mRNA TPM data in the oncoprint

  discussion
  cBioPortal/cbioportal#12340 · Filter by author alisman opened on Sep 15, 2026
  1

• [FEATURE REQUEST] : Patient Genomic Similarity Search API endpoint

  discussionfeature
  cBioPortal/cbioportal#12332 · Filter by author Pradyuman-aviator opened on Sep 4, 2026

• Modernize default clinical track color palettes

  discussion
  cBioPortal/cbioportal#12331 · Filter by author dippindots opened on Sep 3, 2026
  2

• OncoPrint: hex color input and importable color dictionary for clinical tracks

  discussion
  cBioPortal/cbioportal#12330 · Filter by author dippindots opened on Sep 3, 2026

• [BUG]Entity Stable Id Truncated if Contains Dash Character

  bug
  cBioPortal/cbioportal#12329 · Filter by author migbro opened on Sep 3, 2026
  1

  

• [FEATURE REQUEST] Expand survival analysis customization (endpoints, anchor points, left truncation, multivariate/forest plots)

  feature
  cBioPortal/cbioportal#12324 · Filter by author dippindots opened on Sep 1, 2026
  2

• Differentiate between altered, unaltered, and not profiled in the Download tab of Results page

  feature request
  cBioPortal/cbioportal#12323 · Filter by author jjgao opened on Aug 31, 2026
  

• Improve the import flow for single-ClickHouse-instance deployments

  database
  cBioPortal/cbioportal#12317 · Filter by author fuzhaoyuan opened on Aug 27, 2026
  

• Make cBioPortal more resilient to failures in dependent services

  chore
  cBioPortal/cbioportal#12279 · Filter by author dippindots opened on Jul 24, 2026
  5

• Adding more integration tests for cBioPortal's dependent services

  test
  cBioPortal/cbioportal#12278 · Filter by author dippindots opened on Jul 24, 2026
  1

• [FEATURE REQUEST] Allow per-attribute chart type override in study summary (force table vs pie chart)

  feature
  cBioPortal/cbioportal#12259 · Filter by author simonekats opened on Jul 1, 2026

• Langfuse deployment

  devops
  Task

  cBioPortal/cbioportal#12256 · Filter by author dippindots opened on Jun 30, 2026
  

• Add visual cue for uncalled mutations in patient view heatmap

  enhancementgood first issue
  cBioPortal/cbioportal#12232 · Filter by author inodb opened on Jun 19, 2026
  6