Bioinformatics Data Scientist
I am a Bioinformatics Data Scientist with a Master's degree and hands-on experience engineering machine learning pipelines, structural modeling workflows, and multi-omics data infrastructure. My focus is on translating complex biological data into actionable therapeutic insights by building auditable AI evaluation frameworks, automating data pipelines, and optimizing preclinical target safety profiles.
| Category | Tools & Technologies |
|---|---|
| Programming & Data Science | Python, R, Bash, SQL, Git, Statistical Modeling, PyMOL, py3Dmol, VMD |
| AI & Structural Modeling | AlphaFold, AlphaLink2, RAG Pipelines, AI Agents, NAMD, OpenMM, AMBER Tools |
| Genomics & Bioinformatics | RNA-seq, scRNA-seq, DESeq2, Seurat, Genomic Data Mining, TCGA, GTEx |
| Docking & Screening | AutoDock Vina, PyRx, Discovery Studio, ADME Analysis |
| Databases | RCSB-PDB, NCBI, UniProt, ChEMBL, PubChem, DrugBank, DALI Server |
- The Problem: Critical protein-protein interfaces governing oligomerization were hidden, complicating experimental validation.
- The Solution: Predicted dimeric and tetrameric structural states using AlphaLink2 by integrating crosslinking mass spectrometry constraints.
- The Impact: Optimized crosslink-guided modeling parameters to maximize constraint satisfaction and validated model quality using pLDDT and PAE metrics, successfully isolating high-confidence structural target regions.
- Tech Stack: AlphaLink2, Mass Spectrometry Data, Structural Bioinformatics.
- The Problem: A lack of standardized data formatting and centralized access hindered cross-functional research reproducibility.
- The Solution: Compiled, curated, and launched a centralized, public Death Domain Fold (DDF) database featuring 209 entries (www.deathdomain.org).
- The Impact: Automated the pipeline by integrating AlphaFold models with the DPAM tool via custom Python scripts, standardizing the structural biology workflow and dramatically cutting time-to-delivery.
- Tech Stack: Python, AlphaFold, DPAM.
- Master of Science in Bioinformatics | Northeastern University, Boston, MA (Dec 2025)
- Leadership: Graduate Student Ambassador
