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Hi, I'm Neranjan Dissanayake πŸ‘‹

Medical Doctor | Vascular Clinical Research | AI/ML | Biomedical IoT | Digital Health

I am a medical doctor working in a consultant-led vascular surgery service, with extensive hands-on experience in venous intervention and vascular ultrasound.

My research interest is at the intersection of:

Medicine Γ— Vascular Science Γ— Artificial Intelligence Γ— Biomedical Engineering Γ— IoT

I am particularly interested in developing intelligent, patient-centred biomedical systems that combine clinical data, medical imaging, physiological sensing and AI to improve diagnosis, treatment selection and longitudinal monitoring.


πŸ”¬ Research Interests

  • AI-assisted vascular medicine
  • Personalised vascular intervention
  • Medical image analysis
  • Duplex ultrasound and vascular imaging
  • Clinical machine learning
  • Biomedical IoT (IoMT)
  • Wearable physiological sensing
  • Digital twins in healthcare
  • Clinical decision-support systems
  • Autonomous biomedical experimentation
  • Healthcare interoperability and HL7 FHIR
  • Translational medical technology

Current research direction

AI-enabled personalised vascular intervention and intelligent vascular monitoring

A long-term goal is to develop systems that connect:

Clinical data
      ↓
Medical imaging
      ↓
Physiological sensing
      ↓
IoT / Edge devices
      ↓
AI / Machine Learning
      ↓
Patient-specific modelling
      ↓
Clinical decision support
      ↓
Continuous monitoring

🩺 Clinical Background

I work in a vascular surgery environment with substantial experience in venous disease and vascular assessment.

Procedural experience

  • 1,000+ EVLA procedures
  • Hundreds of foam sclerotherapy procedures
  • Hundreds of phlebectomies
  • Hundreds of vascular duplex ultrasound examinations

These clinical experiences have motivated my interest in understanding how AI, sensing and computational modelling can be translated into practical vascular care.


🧠 Research & Technical Interests

Artificial Intelligence & Data Science

  • Python
  • R
  • Machine Learning
  • Statistical modelling
  • Logistic regression
  • Generalized Linear Models
  • Mixed-effects modelling
  • Predictive modelling
  • Time-series analysis
  • Explainable AI
  • Clinical decision-support systems

Biomedical & Healthcare Technology

  • ESP32 / embedded systems
  • Biomedical sensors
  • IoT / IoMT
  • BLE / Wi-Fi
  • MQTT
  • Physiological signal processing
  • PPG / ECG
  • HL7 FHIR
  • Healthcare interoperability
  • Edge computing

Software & Infrastructure

  • Python
  • TypeScript
  • JavaScript
  • React
  • Next.js
  • Django
  • FastAPI
  • PostgreSQL
  • MySQL
  • REST APIs
  • Linux
  • Docker
  • Git / GitHub

πŸš€ Selected Projects

🧬 TB-Predict-ML

An end-to-end clinical prediction and statistical modelling project demonstrating reproducible machine-learning and statistical workflows for medical research.

Focus:

  • Clinical predictive modelling
  • Logistic regression
  • Machine learning
  • Statistical validation
  • R/Python integration
  • Reproducible research

View repository β†’


πŸ“‘ IoMT Clinical FHIR Pipeline

A prototype healthcare IoT architecture connecting physiological sensing, edge computing, clinical telemetry and HL7 FHIR-based interoperability.

Physiological Sensor
        ↓
ESP32 / Edge Device
        ↓
Signal Processing
        ↓
Telemetry
        ↓
FHIR
        ↓
Healthcare System

Focus:

  • Biomedical IoT
  • PPG signal processing
  • Heart-rate estimation
  • SpOβ‚‚ estimation
  • Edge computing
  • HL7 FHIR
  • Clinical interoperability

View repository β†’


πŸ”­ Future Research Projects

Vascular AI

Development of machine-learning systems using:

duplex ultrasound + clinical data + venous anatomy + treatment parameters

to predict:

  • treatment success
  • recurrence
  • recanalisation
  • complications
  • patient outcomes

Intelligent Venous Intervention

A future clinical decision-support platform for personalised selection of venous interventions such as:

EVLA | foam sclerotherapy | phlebectomy | other endovenous treatments

Vascular Digital Twin

Development of patient-specific computational models combining:

ultrasound + anatomy + haemodynamics + clinical data

to simulate and predict treatment outcomes.

Intelligent Vascular Monitoring

Combining:

wearable sensors + IoT + physiological signals + AI

for longitudinal monitoring after vascular intervention.


πŸ“š Research Philosophy

I am interested in research that moves beyond prediction toward real-world clinical translation.

My long-term vision is:

        Clinical Problem
               ↓
          Hypothesis
               ↓
       AI / Computational Model
               ↓
        Biomedical Prototype
               ↓
       IoT / Sensor Data
               ↓
        Clinical Validation
               ↓
        Real-world Translation

I believe the future of biomedical research will increasingly combine clinical expertise, artificial intelligence, engineering and autonomous experimentation.


🎯 Long-Term Research Goal

To develop internationally relevant research in:

Intelligent Vascular Biomedical Engineering

with applications in vascular disease, personalised intervention, medical imaging, physiological sensing and AI-enabled clinical decision support.

I am particularly interested in collaborating with researchers in:

vascular surgery β€’ biomedical engineering β€’ medical imaging β€’ artificial intelligence β€’ digital health β€’ computational modelling β€’ medical devices


πŸ“ˆ Current Learning

I am continuously developing skills in:

  • Advanced clinical statistics
  • Machine learning
  • Deep learning
  • Medical image analysis
  • Signal processing
  • Biomedical engineering
  • Embedded systems
  • Digital twins
  • Causal inference
  • Clinical research methodology

🀝 Research Collaboration

I am interested in research collaborations involving:

  • Clinical AI
  • Vascular imaging
  • AI-assisted intervention
  • Biomedical sensors
  • Healthcare IoT
  • Digital twins
  • Medical-device development
  • Translational biomedical engineering

Open to collaboration with clinicians, engineers, data scientists, biomedical researchers and research institutions.


πŸ“« Contact

GitHub:
https://github.com/neranjandissanayake

I am interested in connecting with researchers working at the intersection of vascular medicine, AI, biomedical engineering and intelligent healthcare systems.


From clinical experience to intelligent biomedical systems.

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