Verified: 2026-09-18 This is a differential update of the previous version (https://hackmd.io/zTFMecEjQzSx2WY-IQrIXw ). Not every endpoint in the main table was re-probed each cycle (most are not directly reachable from this environment and were checked via web sources). Completeness is not claimed; open items are listed at the end.
Subject areas have been normalized to English controlled/established vocabulary (previous mixed Japanese/English values replaced after confirming meaning).
| MCP server | Subject area | Public remote endpoint | Provider | Remote type | Auth / notes |
|---|---|---|---|---|---|
| Ask Helena Public Knowledge | genomics; biomedical knowledge; information retrieval | https://api.helena.bio/ask/v1/mcp |
Helena Bioinformatics | official-public | No auth, read-only. Search with source citations. Sources: Helena llms resource, MCPBeat: Ask Helena |
| EMBL-EBI Ontology Lookup Service (OLS) MCP | biomedical ontologies; ontology search; semantic search | https://www.ebi.ac.uk/ols4/api/mcp |
EMBL-EBI | official-public | Streamable HTTP, no auth. GO/EFO/HPO/MONDO/ChEBI etc. Sources: EMBL-EBI OLS MCP, OLS4 GitHub |
| Expasy SPARQL Assistant MCP | RDF data integration; SPARQL query generation; proteins | https://chat.expasy.org/mcp |
SIB Swiss Institute of Bioinformatics | official-public | Official repo states the public server URL explicitly. Assists SPARQL query generation/execution over SIB endpoints (UniProt/Bgee/OMA/SwissLipids/Cellosaurus etc.). No auth. Public endpoint confirmed in official repo on 2026-09-18. Source: sib-swiss/sparql-llm |
| fanta.bio MCP | functional genomics; cis-regulatory elements; transcription factor binding; gene expression | https://mcp.fanta.bio/mcp |
fanta.bio | official-public | Streamable HTTP (JSON-RPC 2.0), no auth (per-endpoint hourly rate limits: 500/hr lookups, 100/hr full-text, 50/hr batch). CREs, genes, SNPs and TF binding for human (hg38) / mouse (mm10), cross-referenced with SCREEN cCRE / ChIP-Atlas / Ensembl / GWAS. 19 tools, 5 prompts, 2 resources. Docs at docs.fanta.bio/mcp/; transport endpoint mcp.fanta.bio/mcp. Source: fanta.bio MCP docs |
| Folklore Variant Evidence MCP | genetic variation; variant interpretation; human genome | https://api.helena.bio/folklore/v1/mcp |
Helena Bioinformatics | official-public | Read-only, no auth. GRCh38 germline variant evidence. Source: Folklore integrations |
| GWAS Catalog MCP | genome-wide association study; genetic variation; phenotypes | https://ebi.ac.uk/gwas/mcp |
GWAS Catalog / EMBL-EBI | official-public | Official hosted version, no install required. Source: GWAS Catalog MCP |
| Open Targets Platform MCP | target–disease associations; drug discovery | https://mcp.platform.opentargets.org/mcp |
Open Targets | official-public | Official, no auth. Source: Open Targets Platform MCP |
| PubMed MCP — Anthropic life-sciences | literature search | https://pubmed.mcp.claude.com/mcp |
Anthropic | official-public | No auth. Source: Anthropic life-sciences |
| STRING MCP | protein interactions; functional enrichment; sequence similarity | https://mcp.string-db.org/ |
STRING (meringlab) | official-public | Updated: previously "in development" → now documented as a production service. Streamable HTTP. STRING Chat (https://string-db.org/cgi/chat) is a working example that uses this MCP. Third-party health check reported "Healthy" on 2026-09-13. Repo: meringlab/string-mcp. Sources: STRING Help: MCP, mcp.string-db.org, Glama health check |
| TogoMCP | life-science data integration; RDF/SPARQL; identifier mapping | https://togomcp.rdfportal.org/mcp |
DBCLS | official-public | Confirmed live via initialize probe on 2026-09-18 (serverInfo TogoMCP: RDF Portal MCP Server v2.19.0, no auth). Integrates 20+ DBs/APIs. Sources: TogoMCP, 2026-09-18 endpoint probe |
| Synapse MCP | research data management; data sharing | https://mcp.synapse.org/mcp |
Sage Bionetworks | official-auth | OAuth2. Source: Synapse MCP |
| BioContextAI Knowledgebase MCP | data integration; proteins; pathways; protein interactions | https://mcp.biocontext.ai/mcp/ |
BioContextAI | community-public | Public remote service, fair-use limits. Integrates UniProt/Reactome/STRING/InterPro/PRIDE/Open Targets etc. Source: BioContextAI Knowledgebase |
| Cellosaurus MCP — QuentinCody | cell lines; cross-references | https://cellosaurus-mcp-server.quentincody.workers.dev/mcp |
QuentinCody / community | community-public-likely | Community implementation of the SIB Cellosaurus API. Cloudflare Workers deployment domain is stated, but a deployed and ready claim is weaker, so treated at lower confidence. Not the official Cellosaurus MCP. Source: Cellosaurus MCP GitHub |
| ClinPGx MCP — QuentinCody | pharmacogenomics; drug–gene interactions; clinical guidelines | https://clinpgx-mcp-server.quentincody.workers.dev/mcp |
QuentinCody | community-public | README states a deployed remote endpoint. CPIC/DPWG guidelines. Not the official ClinPGx MCP. Source: ClinPGx MCP GitHub |
| Ensembl MCP — cyanheads | genomics; sequence analysis; variant effect prediction; orthologs | https://ensembl.caseyjhand.com/mcp |
cyanheads | community-public | Public hosted instance. Source: cyanheads/ensembl-mcp-server |
| Europe PMC MCP — QuentinCody | literature search; full-text mining; citations | https://europepmc-mcp-server.quentincody.workers.dev/mcp |
QuentinCody | community-public | README states a public remote endpoint. Not the official Europe PMC MCP. Source: Europe PMC MCP GitHub |
| FDA Purple Book MCP — QuentinCody | biologics; biosimilars; drug regulation | https://fda-purple-book-mcp-server.quentincody.workers.dev/mcp |
QuentinCody | community-public | README states a public remote endpoint. Not an official FDA MCP. Source: FDA Purple Book MCP GitHub |
| IEDB MCP — QuentinCody | immunology; immune epitopes; MHC binding | https://iedb-mcp-server.quentincody.workers.dev/mcp |
QuentinCody | community-public | README states a deployed remote endpoint. Not the official IEDB MCP. Source: IEDB MCP GitHub |
| PubMed MCP — cyanheads | literature search; information retrieval | https://pubmed.caseyjhand.com/mcp |
cyanheads | community-public | Public hosted instance. PubMed / Europe PMC / PMC / Unpaywall. Source: cyanheads/pubmed-mcp-server |
| UniProt MCP — cyanheads | proteins; sequence analysis; taxonomy; identifier mapping | https://uniprot.caseyjhand.com/mcp |
cyanheads | community-public | Public hosted instance. Uses the UniProt REST API. Source: cyanheads/uniprot-mcp-server |
| BioStudies MCP — Pipeworx | research data; information retrieval | https://gateway.pipeworx.io/biostudies/mcp |
Pipeworx | gateway | Hosted MCP on the Pipeworx gateway. EMBL-EBI BioStudies search and study metadata. Not the official EMBL-EBI MCP. Source: Pipeworx BioStudies documentation |
| GWAS Catalog MCP — Pipeworx | genome-wide association study; genetic variation; phenotypes | https://gateway.pipeworx.io/gwas-catalog/mcp |
Pipeworx | gateway | Separate implementation from the EBI official version. Source: Pipeworx GWAS Catalog MCP |
| Genomic Intelligence MCP | regulatory genomics; gene expression; sequence analysis | https://mcp.genomicintelligence.ai/mcp |
Genomic Intelligence | commercial-public | Public demo available; API key extends quota. Predicts promoter/splice/enhancer/chromatin/expression. Source: Genomic Intelligence MCP |
| AdisInsight MCP | drug pipeline intelligence; clinical trials; pharmacovigilance | https://adisinsight-mcp.springer.com/mcp |
Springer Nature | commercial-auth | OAuth 2.0, for AdisInsight subscribers. Sources: AdisInsight MCP, AdisInsight |
| BioRender MCP | scientific illustration; figure generation | https://mcp.services.biorender.com/mcp |
BioRender | commercial-auth | Official MCP connector. Authenticate with a BioRender account. Template/icon search, figure generation. Sources: BioRender MCP connector, Claude Connector Directory |
| Consensus MCP | literature search; systematic review; evidence synthesis | https://mcp.consensus.app/mcp |
Consensus | commercial-auth | OAuth or Bearer token. Sources: Consensus MCP documentation, Consensus MCP |
| Cortellis Regulatory Intelligence MCP | regulatory intelligence; drug regulation; medical devices | https://api.clarivate.com/lifesciences/mcp-regulatory/mcp |
Clarivate | commercial-auth | Streamable HTTP, OAuth 2.0. Requires a Cortellis Regulatory Intelligence subscription. Sources: Clarivate MCP documentation, Clarivate announcement |
| Medidata MCP | clinical trials; clinical research; site selection | https://mcp.imedidata.com/mcp |
Medidata Solutions | commercial-auth | Official MCP. Platform Help and Intelligent/Predictive Site Ranking etc. Requires Medidata credentials. Sources: Medidata + Anthropic MCP, Claude Connector Directory |
| Owkin MCP | digital pathology; histopathology; survival analysis | https://mcp.k.owkin.com/mcp |
Owkin | commercial-auth | Requires Owkin credentials. Sources: Owkin announcement, Claude Connector Directory |
| PatSnap Biology Modality MCP | biological sequences; antibodies; proteins; patent search | https://connect.patsnap.com/06e741/logic-mcp?apikey=<API_KEY> |
PatSnap | commercial-auth | Official remote MCP. API key required. Source: PatSnap Biology Modality MCP |
| PatSnap Chemical Molecular MCP | cheminformatics; small molecules; ADMET | https://connect.patsnap.com/713886/logic-mcp?apikey=<API_KEY> |
PatSnap | commercial-auth | Official remote MCP. API key required. Source: PatSnap Chemical Molecular MCP |
| PatSnap Clinical Trials MCP | clinical trials; drug development; competitive intelligence | https://connect.patsnap.com/051cd3/logic-mcp?apikey=<API_KEY> |
PatSnap | commercial-auth | Official remote MCP. API key required. Source: PatSnap Clinical Trials MCP |
| PatSnap Company & Deal Intelligence MCP | business intelligence; licensing; mergers and acquisitions | https://connect.patsnap.com/1f8934/logic-mcp?apikey=<API_KEY> |
PatSnap | commercial-auth | Official remote MCP. API key required. Source: PatSnap Company & Deal Intelligence MCP |
| PatSnap Drug & Asset MCP | drug assets; drug development; targets | https://connect.patsnap.com/30cd71/logic-mcp?apikey=<API_KEY> |
PatSnap | commercial-auth | Official remote MCP. API key required. Source: PatSnap Drug & Asset MCP |
| PatSnap Pharma Intelligence MCP | drug pipeline intelligence; drug development; competitive intelligence | https://connect.patsnap.com/096456/logic-mcp?apikey=<API_KEY> |
PatSnap | commercial-auth | Official remote MCP. API key required. Source: PatSnap Pharma Intelligence MCP |
| PatSnap Regulatory & Guidelines MCP | drug regulation; clinical guidelines | https://connect.patsnap.com/6415c2/logic-mcp?apikey=<API_KEY> |
PatSnap | commercial-auth | Official remote MCP. API key required. Source: PatSnap Regulatory & Guidelines MCP |
| PatSnap Scientific & Translational Evidence MCP | translational research; target validation; clinical evidence | https://connect.patsnap.com/9c333c/logic-mcp?apikey=<API_KEY> |
PatSnap | commercial-auth | Official remote MCP. API key required. Source: PatSnap Scientific & Translational Evidence MCP |
| PatSnap Target & Disease MCP | target biology; disease; epidemiology | https://connect.patsnap.com/2a2645/logic-mcp?apikey=<API_KEY> |
PatSnap | commercial-auth | Official remote MCP. API key required. Source: PatSnap Target & Disease MCP |
| Seqera MCP | bioinformatics workflows; workflow execution; sequence data retrieval | https://mcp.seqera.io/mcp |
Seqera | commercial-auth | OAuth 2.1 / PAT. Nextflow/nf-core, SRA/ENA/GEO. Source: Seqera MCP documentation |
| Wiley Scholar Gateway MCP | literature search; information retrieval; evidence synthesis | https://connector.scholargateway.ai/mcp |
Wiley / Scholar Gateway | commercial-auth | OAuth 2.1, CONNECT SSO. Institutional subscription or trial. Sources: Wiley Scholar Gateway documentation, Wiley AI Solutions |
| Benchling MCP | electronic laboratory notebook; research data management | https://<tenant>.mcp.benchling.com/mcp |
Benchling | tenant-specific | Tenant-specific, OAuth 2.1. Source: Benchling MCP configuration |
| SHARP-on-MCP .NET | health data interoperability; FHIR | https://dotnet.fhir-mcp.promptopinion.ai/mcp |
SHARP-on-MCP | test | Public test environment. Source: SHARP-on-MCP |
| SHARP-on-MCP TypeScript | health data interoperability; FHIR | https://ts.fhir-mcp.promptopinion.ai/mcp |
SHARP-on-MCP | test | Public test environment. Source: SHARP-on-MCP |
| Candidate | Subject area | Candidate endpoint | Provider | Reason held | Next to confirm | Source |
|---|---|---|---|---|---|---|
| CIViC MCP | cancer genomics; somatic variants; clinical interpretation | https://civic-mcp-server.quentincody.workers.dev/mcp |
Griffith Lab / QuentinCody | Paper now peer-reviewed and published (updated). The official chat https://civicdb.org/mcp-chat is a web UI, not an MCP transport endpoint. The Workers URL is presented in README/Glama as "replace with your own subdomain" = a deployment template, so a permanent public endpoint cannot be confirmed. |
Whether civicdb.org exposes a hosted transport endpoint reachable by a standard MCP client, or whether the Workers URL is an author-operated permanent service | griffithlab/civic-mcp-server, Schimmelpfennig et al. 2026, Bioinform Adv |
| Identifiers.org MCP | identifier resolution; compact identifiers; data integration | https://resolver.api.identifiers.org/sse |
EMBL-EBI (Identifiers.org) | Exists as a Claude connector (has connection history, SSE transport), but no primary-source MCP documentation could be confirmed, and the endpoint could not be probed from this environment (domain reachability limits). | Official Identifiers.org / EMBL-EBI MCP page; endpoint probe | Claude connector directory (connection history) |
| PubDictionaries MCP | text annotation; dictionaries; named entity recognition | https://pubdictionaries.org/mcp |
DBCLS (PubDictionaries) | Exists as a Claude connector (has connection history), but no primary-source MCP documentation could be confirmed, and the endpoint could not be probed from this environment. | Official PubDictionaries MCP page; endpoint probe; whether auth is required | Claude connector directory (connection history) |
| GrEBI (Graphs@EBI) MCP | biomedical knowledge graph; data integration | https://www.dev.ebi.ac.uk/kg |
EMBL-EBI (EBISPOT) | The paper states a publicly accessible MCP server, but the URL is given as an API/MCP base URL and it is unclear whether it is the transport endpoint itself. Not re-verified this round (carried forward as-is). | Exact MCP transport path; permanence of the dev domain |
GrEBI GitHub, McLaughlin et al. 2026 |
No changes this round (carried forward as-is; individual items not re-verified).
| MCP | Subject area | Remote use / status |
|---|---|---|
| BioMCP | cancer genomics; genetic variation; clinical trials; literature search | Streamable HTTP supported; no official public hosted endpoint confirmed |
| Galaxy MCP | bioinformatics workflows; tool execution | /api/mcp supported; enablement on public Galaxy instances is instance-dependent |
| GEOmcp | gene expression; sequence data retrieval | HTTP server supported; no public standing endpoint confirmed |
| PLSDB MCP | plasmids; sequence databases | Primarily stdio/self-hosted |
| UCSC Cell Browser MCP | single-cell transcriptomics | Primarily stdio/self-hosted |
| scmcp | single-cell transcriptomics; data analysis | Streamable HTTP supported; self-hosted |
| CellRank MCP | single-cell transcriptomics; trajectory inference | Streamable HTTP supported; self-hosted |
| BioinfoMCP | bioinformatics; command-line tool integration | local/Docker deployment |
| ProteinMCP | protein engineering | MCP framework/tool ecosystem |
| Coala | workflow conversion (CWL → MCP) | generic self-hosted MCP server |
| Holy Bio MCP | bioinformatics (collection) | Primarily local/stdio |
| 10x Genomics MCP | single-cell transcriptomics; spatial transcriptomics | MCPB/local distribution |
| ToolUniverse | scientific tools (collection) | MCPB/local distribution |
- Added (main table):
- Expasy SPARQL Assistant MCP (SIB, official-public) — public endpoint confirmed in official repo
- Updated:
- STRING MCP — previously "in development" → now documented as a production service; source changed to
string-db.org/help/mcp/; repo and health check added - TogoMCP — re-confirmed live on 2026-09-18 (v2.19.0)
- Normalized the
Subject areacolumn across the whole main table to English controlled/established vocabulary (resolved Japanese/English mixing)
- STRING MCP — previously "in development" → now documented as a production service; source changed to
- Added to / updated in the held table:
- CIViC MCP — reflected the peer-reviewed publication and official chat, but held pending an unconfirmed MCP transport endpoint
- Identifiers.org MCP, PubDictionaries MCP
- Removed: none
- Evidence-only updates: STRING source URL
- Confirmed unchanged: self-hosted table, 13 entries (individual items not re-verified; previous state retained)
- Wikidata MCP (
https://wd-mcp.wmcloud.org/mcp) — a general-purpose knowledge base without a primarily life-science-specific function; out of scope. - Apify-hosted EBI scrapers (OLS/Proteins/BioStudies etc.,
mcp.apify.com) — Actor wrappers hosted by Apify that require an Apify account/OAuth; a gateway type. Not EMBL-EBI official and are scraper implementations, so not added this round (can be listed separately in a gateway table if needed). - cBioPortal MCP (
docs.cbioportal.org/ai-integrations/mcp) — cancer genomics. Official docs state "prototypes / work in progress" and no hosted remote endpoint is confirmed, so treated as self-hosted/in-development (re-check next round).
- Many of the commercial/community endpoints in this table are not directly reachable from this environment and were confirmed only via web information (official docs/repos/third-party health checks).
- Identifiers.org and PubDictionaries have Claude connector connection history, but their MCP endpoints are not yet confirmed against primary sources and are therefore held.
- GrEBI and the self-hosted table were not individually re-verified this round; their previous state is retained. Endpoint probing and official-path confirmation are recommended next round.
- No claim of covering "all MCPs worldwide." Discovery sources: official docs/repos, papers (PMC/bioRxiv), Glama/mcpservers.org/MCPBeat, Claude connector directory, GitHub.